MyFol 400-RG Pharmaceutica

Tariq Haider RG Pharmaceutica  made the medicine L-Methylfolate with the name of MyFol 400 Folate is a general term that refers to compounds not only structurally but also with activity similar to that of folic acid. Folic acid (2-amino-4-hydroxy-6-metilenoaminobenzoil-glutamic acid), also known as pteroylglutamic acid, vitamin B9 and vitamin F, is naturally present in foods, generally, in reduced form, such as polyglutamates derivatives with 2 to 7 glutamic acid residues known as folates. To be used by our body folic acid must be converted to its active form - 5-MTHF.

High levels of homocysteine ​​involve the cardiovascular system disorders including thrombosis, stroke, atherosclerosis and myocardial infarction. 5-MTHF in addition to reducing the levels of homocysteine ​​in the blood, also enhances blood flow in peripheral arteries, thus increasing nitric oxide (NO) in the vascular endothelium. Most risk factors for atherosclerosis are associated with deficiency in vasodilation due to insufficient production of NO (chronic exposure of vascular endothelial cells to homocysteine ​​compromises the proper production of NO), this leads to endothelial injury and the onset of atherosclerosis, including increased adhesion of monocytes and platelets, increased smooth muscle proliferation and thrombus formation. 5-MTHF enhances synthesis.

 Reduction of homocysteine ​​plasma levels, thereby increasing the availability of endothelial cofactors such as tetrahydrobiopterin;